PROS1 / Protein S Protein|报价|厂家现货

PROS1 / Protein S蛋白产品信息

别名: PROS1, PROS
表达方式: 
A DNA sequence encoding the human PROS1 (P07225) (Met1-Ser676) was expressed with a polyhistidine tag at the C-terminus.
种属: Human
表达宿主: Human Cells

PROS1 / Protein S Protein QC Testing

纯度: > 95 % as determined by SDS-PAGE SDS-PAGE
内**: < 1.0 EU per μg of the protein as determined by the LAL method
稳定性: Samples are stable for up to twelve months from date of receipt at -70℃
预测N端: Asn 25
分子量: 
The recombinant human PROS1 consists of  663 amino acids and predicts a molecular mass of  74.1 KDa. It migrates as an approximately 69-89 KDa band in SDS-PAGE under reducing conditions.
缓冲液: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
Please contact us for any concerns or special requirements.

PROS1 / Protein S Protein Usage Guide

储存方法: Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution: A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.

PROS1 / Protein S蛋白背景综述

PROS1, also known as protein S, is a vitamin K-dependent plasma protein that functions as a cofactor for the anticoagulant protease, activated protein C (APC) to inhibit blood coagulation. PROS1 has two isoforms: a free, functionally active form and an inactive form complexed with C4b-binding protein. Besides its anticoagulant function, PROS1 also acts as an agonist for the tyrosine kinase receptors Tyro3, Axl, and Mer. The endothelium expresses Tyro3, Axl, and Mer and produces protein S. The interaction of protein S with endothelial cells and particularly its effects on angiogenesis have not yet been analyzed.

参考文献

Beauchamp NJ. et al., 2004, Br J Haematol. 125 (5): 647-54.
García de Frutos P. et al., 2007, Thromb Haemost. 98 (3): 543-56.
Rezende SM. et al., 2004, Blood. 103 (4): 1192-201.

规格：100ug

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