BPIFB1 / LPLUNC1蛋白产品信息
别名: BPIFB1, C20orf114, LPLUNC1 表达方式: A DNA sequence encoding the human BPIFB1 (AAH08429.1) (Met1-Gln484) was expressed with a polyhistidine tag at the C-terminus. 种属: Human 表达宿主: Human Cells BPIFB1 / LPLUNC1 Protein QC Testing
纯度: > 95 % as determined by SDS-PAGE SDS-PAGE 内**: < 1.0 EU per μg of the protein as determined by the LAL method 稳定性: Samples are stable for up to twelve months from date of receipt at -70℃ 预测N端: Thr 22 分子量: The recombinant human BPIFB1 consists of 474 amino acids and predicts a molecular mass of 51.7 KDa. It migrates as an approximately 53 KDa band in SDS-PAGE under reducing conditions. 缓冲液: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA. Please contact us for any concerns or special requirements. BPIFB1 / LPLUNC1 Protein Usage Guide
储存方法: Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. Reconstitution: A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information. BPIFB1 / LPLUNC1蛋白背景综述
BPIFB1, also known as LPLUNC1, belongs to the BPI/LBP/Plunc superfamily, plunc family. BPIFB1 may be involved in the innate immune response to bacterial exposure in the mouth, nasal cavities, and lungs. BPIFB1 is expressed in the upper respiratory tract and oral cavity, which may function in host defence. The expression of BPIF proteins is associated with CF lung disease in humans and mice. It is unclear if this elevation of protein production, which results from phenotypic alteration of the cells within the diseased epithelium, plays a role in the pathogenesis of the disease. BPIFB1 is an abundant, secreted product of goblet cells and minor mucosal glands of the respiratory tract and oral cavity and suggest that the protein functions in the complex milieu that protects the mucosal surfaces in these locations. 参考文献
Bingle CD. et al., 2011, Biochem Soc Trans. 39 (4): 977-83. Shin OS. et al., 2011, J Infect Dis. 204 (9): 1349-57. Bingle L. et al., 2012, Histochem Cell Biol. 138 (5): 749-58. 规格:10ug 关 键 词:BPIFB1 / LPLUNC1 Protein,BPIFB1 / LPLUNC1蛋白质,使用说明,现货,实验室耗材,生化试剂,上海创赛,博飞美科,实验仪器,厂家
CANSPEC品质提供的BPIFB1 / LPLUNC1 Protein|BPIFB1 / LPLUNC1蛋白质|使用说明|现货性能**,其优良的品质满足您不同实验的多种需求。
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