Rat CLEC4B2 / Mdcar1 Protein|鼠CLEC4B2 / Mdcar1蛋白质|厂家现货|参数

CLEC4B2 / mDCAR1蛋白产品信息

别名: CLEC4B2, Aplra1
表达方式: 
A DNA sequence encoding the rat CLEC4B2 (Q67DU9) (Met44-Leu208) was expressed with a polyhistidine tag at the N-terminus.
种属: Rat
表达宿主: Human Cells

CLEC4B2 / mDCAR1 Protein QC Testing

纯度: > 85 % as determined by SDS-PAGE SDS-PAGE
内**: < 1.0 EU per μg of the protein as determined by the LAL method
稳定性: Samples are stable for up to twelve months from date of receipt at -70℃
预测N端: His
分子量: 
The recombinant rat CLEC4B2 comprises 185 amino acids and has a predicted molecular mass of 21.8 kDa. The apparent molecular mass of the protein is approximately 31-36 kDa in SDS-PAGE under reducing conditions.
缓冲液: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
Please contact us for any concerns or special requirements.

CLEC4B2 / mDCAR1 Protein Usage Guide

储存方法: Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution: A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.

CLEC4B2 / mDCAR1蛋白背景综述

Clec4b2, also known as mDCAR1, is a member of the DCIR/DCAR family. Expression of Clec4b2 was strongly tissue dependent. Clec4b2 expression on DCs was restricted to the CD8(+) DC subset in spleen and thymus and on subpopulations of CD11b(+) myeloid cells in bone marrow and spleen, whereas the molecule was not detectable on both cell types in lymph nodes and peripheral blood. Clec4b2 is a functional receptor on cells of the immune system and provides further insights into the regulation of immune responses by CLRs.

参考文献

Katayama S. et al., 2005, Science. 309 (5740): 1564-6.
Kaden SA. et al., 2009, J Immunol. 183 (8): 5069-78.
Skarnes WC. et al., 2011, Nature. 474 (7351): 337-42.

规格：10ug

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