Cynomolgus ADAM8 Protein|技术资料|厂家现货

ADAM8蛋白产品信息

别名: ADAM8
表达方式: 
A DNA sequence encoding the cynomolgus ADAM8 (XP_002805919.1) (Met1-Pro497) was expressed with a polyhistidine tag at the C-terminus.
种属: Cynomolgus
表达宿主: Human Cells

ADAM8 Protein QC Testing

纯度: (50.8+34.6) % as determined by SDS-PAGE SDS-PAGE
内**: < 1.0 EU per μg of the protein as determined by the LAL method
稳定性: Samples are stable for up to twelve months from date of receipt at -70℃
预测N端: Arg 21
分子量: 
The recombinant cynomolgus ADAM8 comprises 488 amino acids and has a calculated molecular mass of 53.6 KDa. The apparent molecular mass of it is approximately 47 and 66 KDa  in SDS-PAGE under reducing conditions.
缓冲液: Lyophilized from sterile 12.5mM Tris, 5mM CaCl2, 75mM NaCl, 50% glycerol.
Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
Please contact us for any concerns or special requirements.

ADAM8 Protein Usage Guide

储存方法: Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution: A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.

ADAM8蛋白背景综述

ADAM8, also known as CD156, is a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. ADAM8 is possiblely involved in extravasation of leukocytes As a metalloprotease, ADAM8 also may be involved in cell adhesion during neurodegeneration, and it is thought to be a target for allergic respiratory diseases, including asthma.

参考文献

Yoshiyama K. et al., 1997, Genomics. 41 (1): 56-62.
Schlomann U. et al., 2001, J Neurosci. 20 (21): 7964-71.
Amour A. et al., 2002, FEBS Lett. 524 (1-3): 154-8.

规格：10ug

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