RAB27B Protein|RAB27B蛋白质|使用说明|价格

RAB27B蛋白产品信息

别名: RAB27B
表达方式: 
A DNA sequence encoding the human RAB27B (NP_004154.2) (Thr2-Lys215) was expressed with an N-terminal polyhistidine tag.
种属: Human
表达宿主: Human Cells

RAB27B Protein QC Testing

纯度: > 95 % as determined by SDS-PAGE SDS-PAGE
内**: < 1.0 EU per μg of the protein as determined by the LAL method
稳定性: Samples are stable for up to twelve months from date of receipt at -70℃
预测N端: His
分子量: 
The recombinant human RAB27B comprises 234 amino acids and has a predicted molecular mass of 26.6 kDa. The apparent molecular mass of the protein is approximately 29 kDa in SDS-PAGE under reducing conditions.
缓冲液: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
Please contact us for any concerns or special requirements.

RAB27B Protein Usage Guide

储存方法: Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution: A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.

RAB27B蛋白背景综述

RAB27B is a a regulator of vesicle exocytosis. It delivers proinvasive signals for increased invasiveness, tumor size, and metastasis of various estrogen receptor (ER)-positive breast cancer cell lines, both in vitro and in vivo. In human breast cancer specimens, RAB27B associates with a low degree of differentiation and the presence of lymph node metastasis in ER-positive breast cancer. RAB27B belongs to the Rab protein family which are composed of prenylated, membrane-bound proteins involved in vesicular fusion and trafficking.

参考文献

Hendrix A. et al., 2010, Oncotarget. 1 (4): 304-8.
Tanaka C. et al., 2012, Biochem Biophys Res Commun. 419 (2): 368-73.
Zhang JX. et al., 2012, J Transl Med. 10: 242.

规格：50ug

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