Mouse LY96 / LY-96 / ESOP-1 Protein|使用说明|价格|现货

LY96 / LY-96 / ESOP-1 Protein Product Information

Synonym : LY96, Esop1, Md2
Protein Construction: A DNA sequence encoding the mouse LY96 (Q9JHF9) (Met1-Asn160) was expressed with the Fc region of human IgG1 at the C-terminus.
Source: Mouse
Expression Host: Human Cell

LY96 / LY-96 / ESOP-1 Protein Product Information

Synonym : LY96, Esop1, Md2
Protein Construction: A DNA sequence encoding the mouse LY96 (Q9JHF9) (Met1-Asn160) was expressed with the Fc region of human IgG1 at the C-terminus.
Source: Mouse
Expression Host: Human Cell

LY96 / LY-96 / ESOP-1 Protein QC Testing

Purity: > 95 % as determined by SDS-PAGE SDS-PAGE
Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method
Stability: Samples are stable for up to twelve months from date of receipt at -70℃
Predicted N terminal: Glu 19
Molecular Mass: The recombinant mouse LY96/Fc is a disulfide-linked homodimer. The reduced monomer comprises 383 amino acids and has a predicted molecular mass of 43.4 kDa. The apparent molecular mass of the protein is approximately 47 kDa in SDS-PAGE under reducing conditions.
Formulation: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
Please contact us for any concerns or special requirements.

LY96 / LY-96 / ESOP-1 Protein Usage Guide

Storage:  Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution:  A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.

LY96 / LY-96 / ESOP-1 Protein Description

LY-96, also known as ESOP-1, is a protein which associates with toll-like receptor 4 on the cell surface and confers responsiveness to lipopolysaccyaride (LPS). LY-96 also cooperates with TLR2 in the response to cell wall components from Gram-positive and Gram-negative bacteria. It enhances TLR4-dependent activation of NF-kappa-B. ESOP-1 has 160 amino acids, the sequence of which shows 64% identity with human ESOP-1/MD-2. ESOP-1 mRNA is highly expressed in the mouse embryos at 7.5 days after coitus.

References

Kato K. et al., 2000, Blood. 96 (1): 362-4.
Abreu MT. et al., 2001, J Immunol. 167 (3): 1609-16.
Re Fabio. et al., 2002, J Biol Chem. 277 (26): 23427-32.

规格：50ug

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