C22-103-10 rHuBCMA说明书

Catalog Number: C22-103-10
Source:  Escherichia coli.
Molecular Weight:  Approximately 5.3 KDa, a single non-glycosylated polypeptide chain containing 50 amino acids.
Quantity:  5μg/20μg/1000μg
Purity:  >98% by SDS-PAGE and HPLC analyses.
Biological Activity:  Data Not Available.
Physical Appearance:  Sterile Filtered White lyophilized (freeze-dried) powder.
Formulation:  Lyophilized from a 0.2μm filtered concentrated solution in 30% acetonitrile, 0.1% TFA.
AA Sequence:  AGQCSQNEYF DSLLHACIPC QLRCSSNTPP LTCQRYCNAS VTNSVKGTNA
Endotoxin:  Less than 1EU/μg of rHuBCMA as determined by LAL method.
Reconstitution:  We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the
 bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a
 concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and
 stored at <-20°C. Further dilutions should be made in appropriate buffered solutions.
Storage:  This lyophilized preparation is stable at 2-8°C, but should be kept at -20°C for long term storage,
 preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2-8°C. For
 maximal stability, apportion the reconstituted preparation into working aliquots and store at -20°C to
 -70°C. Avoid repeated freeze/thaw cycles.
Usage:  This material is offered by Shanghai Corning Bio-Tech for research, laboratory or further evaluation purposes. NOT FOR HUMAN USE.

Human B-Cell Maturation Antigen
B-Cell Maturation Antigen (BCMA), a member of the TNF receptor superfamily, binds to BAFF and APRIL. BCMA is
expressed on mature B-cells and other B-cell lines and plays an important role in B cell development, function and regulation.
BCMA also has the capability to activate NF-kappaB and JNK. The human BCMA gene codes for a 184 amino acid type I
transmembrane protein, which contains a 54 amino acid extracellular domain, a 23 amino acid transmembrane domain, and a 107
amino acid extracellular domain.