产品名称:APC-H7 小鼠抗人 CD3 抗体;APC-H7 Mouse Anti-Human CD3
中文名称:APC-H7 小鼠抗人 CD3 抗体
英文名称:APC-H7 Mouse Anti-Human CD3
APC-H7 Mouse Anti-Human CD3 产品介绍:
Material Number: 560176 Alternate Name: CD3-epsilon; CD3E; Leu4; T-cell surface antigen T3/Leu-4 epsilon chain; T3E Size: 100 Tests Vol. per Test: 5 µl Clone: SK7 (also known as Leu-4) Immunogen: Human Thymocytes Isotype: Mouse (BALB/c) IgG1, κ Reactivity: QC Testing: Human Workshop: II T118; III T492 Storage Buffer: Aqueous buffered solution containing BSA, protein stabilizer, and ≤0.09% sodium azide.
The SK7 (Leu-4) monoclonal antibody specifically binds to the epsilon chain of the CD3 antigen/T-cell antigen receptor (TCR) complex. This complex is composed of at least six proteins that range in molecular weight from 20 to 30 kDa. The antigen recognized by CD3 antibodies is noncovalently associated with either α/β or γ/δ TCR (70 to 90 kDa). The CD3 antigen is present on 61% to 85% of normal peripheral blood lymphocytes 60% to 85% of thymocytes and on Purkinje cells in cerebellum. The soluble form of this antibody has a mitogenic effect on most peripheral blood T lymphocytes, provided appropriate functional monocytes are present.
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. The antibody was conjugated with APC-H7 under optimum conditions, and unconjugated antibody and APC-H7 were removed.
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