产品名称:PE 小鼠抗人 HLA-ABC 抗体;PE Mouse anti-Human HLA-ABC
中文名称:PE 小鼠抗人 HLA-ABC 抗体
英文名称:PE Mouse anti-Human HLA-ABC
PE Mouse anti-Human HLA-ABC 产品介绍:
Material Number: 560168 Size: 100 tests Vol. per Test: 20 µl Clone: DX17 Immunogen: Polyclonal Human NK Cell Line Isotype: Mouse IgG1, κ Reactivity: QC testing: Human Storage Buffer: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
The DX17 monoclonal antibody reacts with a monomorphic epitope expressed on all HLA (human leukocyte antigen) class I molecules examined. DX17 immunoprecipitates HLA class I heavy chains (45 kDa) and β2-microglobulin (12kDa) from radiolabeled human cell lines. HLA is determined by a complex segment of the short arm of chromosome 6 and there are many human HLAs encoded in this segment. The antigenic agglomerate is called MHC, for major histocompatibility complex. Examples of class I loci are HLA-A, -B, and -C, which are serologically assayed; class II loci, e.g., HLA-D/DR and DC1, are tested by lymphocytotoxic methods.
The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. The antibody was conjugated with R-PE under optimum conditions, and unconjugated antibody and free PE were removed. Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
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