647 Mouse anti-Human CD337 (NKp30)

产品名称:647 小鼠抗人 CD337 (NKp30) 抗体；647 Mouse anti-Human CD337 (NKp30)

中文名称:647 小鼠抗人 CD337 (NKp30) 抗体

英文名称:647 Mouse anti-Human CD337 (NKp30)

647 Mouse anti-Human CD337 (NKp30) 产品介绍：

Material Number: 558408
Size: 0.1 mg
Concentration: 0.2 mg/ml
Clone: p30-15
Immunogen: Human NKp30 extracellular domain
Isotype: Mouse IgG1, κ
Reactivity: Human
Storage Buffer: Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium 
azide.



647 Mouse anti-Human CD337 (NKp30) Description：

The monoclonal antibody clone p30-15 reacts with CD337, also known as NKp30, a receptor found on the surface of natural killer (NK) cells. NK cells are large lymphoid cells discovered because of their ability to recognize and kill abnormal cells such as tumor and virally infected cells. NK cell immune responses are regulated by a balance of activating and inhibitory signals generated by cell surface receptors. Inhibitory receptors recognize MHC class I molecules on normal cells producing a negative signal to the NK cell. Loss of MHC class I expression in infected or transformed cells results in the loss of this negative signal leading to NK cell activation. In concert with the loss of inhibitory signals, activation signals via NK receptors such as NKp30, NKp44, NKp46, NKG2D, and NKp80 mediate the activation of NK cells. NKp30 cooperates with NKp46 and/or NKp44 in the induction of NK cell-mediated cytotoxicity against the majority of target cells.

The antibody was conjugated to Alexa Fluor® 647 under optimum conditions, and unreacted Alexa Fluor® 647 was removed.
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.