647 Mouse Anti-Human CD282

产品名称:647 小鼠抗人 CD282 抗体；647 Mouse Anti-Human CD282

中文名称:647 小鼠抗人 CD282 抗体

英文名称:647 Mouse Anti-Human CD282

647 Mouse Anti-Human CD282 产品介绍：

Material Number: 558319
Alternate Name: TLR2
Size: 100 tests
Vol. per Test: 20 µl
Clone: 11G7
Immunogen: Human TLR2-transfected cell line
Isotype: Mouse IgG1, κ
Reactivity: QC Testing: Human
Storage Buffer: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

The monoclonal antibody 11G7 reacts with human CD282, which is also known as Toll-like receptor 2 (TLR2). It is primarily expressed by 
peripheral blood monocytes. Toll-like receptors (TLRs) play a critical role in anti-microbial resistance. Moreover, TLRs have been shown to 
activate a number of signal transduction pathways which lead to the induction of genes involved in host defense. TLRs are type-1 
transmembrane receptors characterized by the presence of extracellular leucine-rich repeat and intracellular Toll/IL-1 receptor domains. At 
least 12 mammalian TLRs have been identified, each recognizing a distinct bacterial or viral pathogen-associated molecular pattern, termed 
PAMP. Peptidoglycan from Gram-positive bacteria, lipoproteins and lipopeptides from several bacteria, glycophosphatidylinositol, 
lipoarabinomannan, porins, and zymosan from yeast have been reported to be the ligands for TLR2.

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.