产品名称:APC 小鼠抗人 NKG2D 抗体;APC Mouse Anti-Human NKG2D
中文名称:APC 小鼠抗人 NKG2D 抗体
英文名称:APC Mouse Anti-Human NKG2D
APC Mouse Anti-Human NKG2D 产品介绍:
Material Number: 558071 Size: 100 tests Vol. per Test: 20 µl Clone: 1D11 Isotype: Mouse IgG1, κ Reactivity: QC Testing: Human Workshop: NA Storage Buffer: Aqueous buffered solution containing BSA and ≤0.09% sodium azide. APC Mouse Anti-Human NKG2D Description:
Antibody 1D11 reacts with NKG2D (42 kDa), an activating receptor for MICA encoded within MHC. Different from natural cytotoxicity receptor (NCR), NKG2D expression is not confined to NK cells, it is also present on virtually all TCR γ/δ+ and CD8+TCR α/β+ T cells. NKG2D functions as a triggering receptor involved in natural cytotoxicity mediated by normal NK cells against a variety of tumors or normal target cells. More importantly, NKG2D can complement the role of NCR in tumor cell lysis. Remarkably, the combined maskings of NCR and NKG2D led to a complete inhibition of NK-mediated lysis of all tumor or normal cells.
Store undiluted at -20°C. The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. The antibody was conjugated to APC under optimum conditions, and unconjugated antibody and free APC were removed. Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
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