FITC Mouse Anti-Human CD274

产品名称:FITC 小鼠抗人 CD274 抗体；FITC Mouse Anti-Human CD274

中文名称:FITC 小鼠抗人 CD274 抗体

英文名称:FITC Mouse Anti-Human CD274

FITC Mouse Anti-Human CD274 产品介绍：

Material Number: 558065
Alternate Name: B7-H1, PD-L1
Size: 100 tests
Vol. per Test: 20 µl
Clone: MIH1
Isotype: Mouse IgG1, κ
Reactivity: QC Testing: Human
Storage Buffer: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

FITC Mouse Anti-Human CD274 Description：

PD-L1 and PD-L2 are newly discovered members of the B7 family are the ligands for the program death 1 (PD-1) receptor. They are
expressed on immature dendritic cells and mature dendritic cells. PD-L1, also called B7-H1, is expressed on antigen-presenting cells,
including IFN-γ-stimulated monocytes, and activated human and murine dendritic cells. Monoclonal antibodies that block PD-L1 and PD-L2
on dendritic cells result in enhanced T cell proliferation and cytokine production. PD-L1 is also expressed on placental trophoblasts,
myocardial endothelium, cortical thymic epithelial cells, and on most carcinomas. Studies show overlapping functions of PD-L1 and PD-L2
and indicate an important role for the PD-L:PD-1 pathway in regulating T cell responses.

The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
The antibody was conjugated with FITC under optimum conditions, and unreacted FITC was removed.
Store undiluted at 4° C and protected from prolonged exposure to light. Do not freeze.