647 Rat Anti-Human CD294

产品名称:647 大鼠抗人 CD294 抗体；647 Rat Anti-Human CD294

中文名称:647 大鼠抗人 CD294 抗体

英文名称:647 Rat Anti-Human CD294

647 Rat Anti-Human CD294 产品介绍：

Material Number: 558042
Alternate Name: CRTH2; PTGDR2 ; Prostaglandin D2 receptor 2; DL1R; DP2; GPR44
Size: 0.1 mg
Concentration: 0.2 mg/ml
Clone: BM16
Immunogen: Human CRTH2 Transfected Cell Line
Isotype: Rat (WI) IgG2a, κ
Reactivity: QC Testing: Human
Workshop: VIII
Storage Buffer: Aqueous buffered solution containing ≤0.09% sodium azide.


647 Rat Anti-Human CD294 Description：

The BM16 monoclonal antibody specifically binds to CD294. CD294 is encoded by PTGDR2 (Prostaglandin D2 receptor 2) and is also
known as CRTH2 (chemoattractant receptor-homologous molecule expressed on Th2 cells), GPR44 (G protein-coupled receptor 44), DL1R,
and DP2. CD294 is a member of the G protein-coupled leukocyte chemoattractant receptor family and it is expressed on Th2, but not Th1 type
cells. CD294 is detectable on CD4+ T cells in fresh PBMC but not on B cells and NK cells. CD294 is also expressed on peripheral blood
basophils and eosinophils, suggesting its involvement allergic reactions. Phenotypic analysis of CD4+ T cells expressing CRTH2
demonstrated that they were also CD45RA-negative and CD45RO+ and CD25+. These cells produce Th2- but little or no Th1-type cytokines
upon stimulation with PMA and Ionomycin.

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.