PE Mouse Anti-Human CD274

产品名称:PE 小鼠抗人 CD274 抗体；PE Mouse Anti-Human CD274

中文名称:PE 小鼠抗人 CD274 抗体

英文名称:PE Mouse Anti-Human CD274

PE Mouse Anti-Human CD274 产品介绍：

Material Number: 557924
Alternate Name: B7-H1, PD-L1
Size: 100 tests
Vol. per Test: 20 µl
Clone: MIH1
Isotype: Mouse IgG1, κ
Reactivity: QC Testing: Human
Storage Buffer: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

PE Mouse Anti-Human CD274 Description：

PD-L1 and PD-L2 are newly discovered members of the B7 family are the ligands for the program death 1 (PD-1) receptor. They are
expressed on immature dendritic cells and mature dendritic cells. PD-L1, also called B7-H1, is expressed on antigen-presenting cells,
including IFN-γ-stimulated monocytes, and activated human and murine dendritic cells. Monoclonal antibodies that block PD-L1 and PD-L2
on dendritic cells result in enhanced T cell proliferation and cytokine production. PD-L1 is also expressed on placental trophoblasts,
myocardial endothelium, cortical thymic epithelial cells, and on most carcinomas. Studies show overlapping functions of PD-L1 and PD-L2
and indicate an important role for the PD-L:PD-1 pathway in regulating T cell responses.

The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
The antibody was conjugated with R-PE under optimum conditions, and unconjugated antibody and free PE were removed.
Store undiluted at 4° C and protected from prolonged exposure to light. Do not freeze.