APC-Cy™7 Mouse Anti-Human CD8

产品名称:APC-Cy™7 小鼠抗人 CD8 抗体；APC-Cy™7 Mouse Anti-Human CD8

中文名称:APC-Cy™7 小鼠抗人 CD8 抗体

英文名称:APC-Cy™7 Mouse Anti-Human CD8

APC-Cy™7 Mouse Anti-Human CD8 产品介绍：

Material Number: 557834
Alternate Name: CD8α; CD8A; CD8 alpha; Leu2a; MAL; T8; p32
Size: 100 Tests
Vol. per Test: 5 µl
Clone: SK1
Immunogen: Human Peripheral Blood T Cells
Isotype: Mouse (BALB/c) IgG1, κ
Reactivity: QC Testing: Human
Tested in Development: Rhesus, Cynomolgus, Baboon
Workshop: I T51,74; III T118,152,571
Storage Buffer: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.



APC-Cy™7 Mouse Anti-Human CD8 Description：

CD8 recognizes the 32-kDa a-subunit of a disulfide-linked bimolecular complex. The majority of peripheral blood CD8+ T lymphocytes 
express an a/b heterodimer (Mr 32, 30 kDa), while CD8+CD16+ natural killer (NK) lymphocytes and CD8+ T-cell receptor (TCR)-γ/δ+ 
lymphocytes express a/a homodimer (Mr 30 kDa). CD8+TCR-α/β+ lymphocytes can express either an α/α homodimer or α/β heterodimer. The 
CD8 antigenic determinant binds to class I major histocompatibility (MHC) molecules resulting in increased adhesion between the CD8+ T 
lymphocytes and target cells. Binding of the CD8 antigen is coupled to a protein tyrosine kinase p56lck. The CD8:p56lck complex can play a 
role in T-lymphocyte activation through mediation of the interactions between the CD8 antigen and the CD3/TCR complex. 

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
The antibody was conjugated with APC-Cy7 under optimum conditions, and unconjugated antibody and free APC-Cy7 were removed.