产品名称:PE-Cy™7 小鼠抗人 CD16 抗体;PE-Cy™7 Mouse Anti-Human CD16
中文名称:PE-Cy™7 小鼠抗人 CD16 抗体
英文名称:PE-Cy™7 Mouse Anti-Human CD16
PE-Cy™7 Mouse Anti-Human CD16 产品介绍:
Material Number: 557744 Size: 100 tests Vol. per Test: 5 µl Clone: 3G8 Isotype: Mouse IgG1, κ Reactivity: QC Testing: Human Reported: Baboon, Rhesus, Cynomolgus Workshop: IV N409 Storage Buffer: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
The 3G8 monoclonal antibody specifically binds to the 50-65 kDa transmembrane form of the IgG Fc Receptor (FcγRIII), a human NK-cell-associated antigen. CD16 is expressed on NK cells as well as macrophages and granulocytes. Reports indicate that CD16 plays a role in signal transduction and NK cell activation. The 3G8 antibody blocks the binding of soluble immune complexes to granulocytes.
The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. The antibody was conjugated with PE-Cy7 under optimum conditions, and unconjugated antibody and free PE-Cy7 were removed. Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
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