PE-Cy™7 Mouse Anti-Human CD11b/Mac-1

产品名称:PE-Cy™7 小鼠抗人 CD11b/Mac-1 抗体；PE-Cy™7 Mouse Anti-Human CD11b/Mac-1

中文名称:PE-Cy™7 小鼠抗人 CD11b/Mac-1 抗体

英文名称:PE-Cy™7 Mouse Anti-Human CD11b/Mac-1

PE-Cy™7 Mouse Anti-Human CD11b/Mac-1 产品介绍：

Material Number: 557743
Alternate Name: Mac-1α, integrin αM subunit, CR3 α chain
Size: 100 tests
Vol. per Test: 5 µl
Clone: ICRF44 (also known as 44)
Isotype: Mouse IgG1, κ
Reactivity: QC Testing: Human
Workshop: IV M047
Storage Buffer: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

The ICRF44 monoclonal antibody reacts with CD11b, the 165-kDa adhesion glycoprotein that associates with the 95-kDa integrin β2 (CD18) 
to form the CD11b/CD18 complex, also known as Mac-1 or CR3. CD11b is expressed on activated lymphocytes, monocytes, granulocytes, 
and a subset of NK cells. CD11b functions in cell-cell and cell-substrate interactions and is a receptor for iC3b, CD54 (ICAM-1), CD102 
(ICAM-2) and CD50 (ICAM-3). This antibody significantly inhibits polymorphonuclear leukocyte aggregation in response to fMLP.

The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
The antibody was conjugated with PE-Cy7 under optimum conditions, and unconjugated antibody and free PE-Cy7 were removed.
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.