产品名称:PE-Cy™7 仓鼠抗小鼠 CD95 抗体;PE-Cy™7 Hamster Anti-Mouse CD95
中文名称:PE-Cy™7 仓鼠抗小鼠 CD95 抗体
英文名称:PE-Cy™7 Hamster Anti-Mouse CD95
PE-Cy™7 Hamster Anti-Mouse CD95 产品介绍:
Material Number: 557653 Alternate Name: Fas/APO-1 Size: 0.1 mg Concentration: 0.2 mg/ml Clone: Jo2 Immunogen: WR19L mouse lymphoma cells transformed with recombinant mouse Fas Isotype: Armenian Hamster IgG2, λ2 Reactivity: QC Testing: Mouse Storage Buffer: Aqueous buffered solution containing ≤0.09% sodium azide. PE-Cy™7 Hamster Anti-Mouse CD95 Description:
Fas antigen, CD95, is a 45 kDa cell-surface protein which can mediate apoptosis. It belongs to the TNF (tumor necrosis factor)/NGF receptor family. Expression of Fas has been described in the thymus, liver, heart, lung and ovary. Fas plays an important role in the apoptotic process that takes place during development. Monoclonal antibodies recognizing Fas such as Jo2 have cytolytic activity on cells expressing Fas. The cell death stimulated by Fas antibodies is characteristic of apoptosis and suggests that the lethal effects are a result of interaction of antibody with a functional Fas antigen as opposed to complement-mediated lysis.
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. The antibody was conjugated with PE-Cy7 under optimum conditions, and unconjugated antibody and free PE-Cy7 were removed.
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