DimerX I: Recombinant Soluble Dimeric Mouse CD1d:Ig Fusion Protein

产品名称:DimerX I: Recombinant Soluble Dimeric Mouse CD1d:Ig Fusion Protein

DimerX I: Recombinant Soluble Dimeric Mouse CD1d:Ig Fusion Protein 产品介绍：

Material Number: 557599
Size: 0.25 mg
Concentration: 0.5 mg/ml
Isotype: Mouse IgG1, λ
Storage Buffer: Aqueous buffered solution containing ≤0.09% sodium azide.

The CD1d:Ig fusion protein consists of the extracellular major histocompatibility complex (MHC) class I-like domains of the mouse CD1d 
molecule fused with the VH regions of mouse IgG1 (see figure). Like MHC class I molecules, the CD1d noncovalently associates with β2 
Microglobulin (β2M). For this reason, BD Pharmingen DimerX consists of recombinant CD1d:Ig and β2M. Recombinant CD1d molecules, 
like the DimerX fusion protein, are useful for studying Natural Killer T (NKT)-cell function by immunofluorescent staining and flow 
cytometric analysis of antigen-specific NKT cells. 

Store undiluted at 4°C.
The mouse CD1d:Ig fusion protein was expressed together with mouse β2M in the mouse plasmacytoma cell line, J558L 
(ATCC TIB-6). The CD1d:Ig and β2M polypeptide chains are associated noncovalently as a consequence of their coexpression 
within J558L cells. The CD1d:Ig fusion protein was purified from tissue culture supernatant by affinity chromatography. The 
purity of the preparation was confirmed by SDS-PAGE. The CD1d:Ig has been tested by ELISA to verify the fusion protein.

DimerX I: Recombinant Soluble Dimeric Mouse CD1d:Ig Fusion  Protein Suggested Companion Products：

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554656 Stain Buffer (FBS) 500 ml (none)