产品名称:PE 小鼠抗人 CD11b 抗体;PE Mouse Anti-Human CD11b
中文名称:PE 小鼠抗人 CD11b 抗体
英文名称:PE Mouse Anti-Human CD11b
PE Mouse Anti-Human CD11b 产品介绍:
Material Number: 557321 Alternate Name: Mac-1, CR3 Size: 50 tests Vol. per Test: 20 µl Clone: ICRF44 Isotype: Mouse IgG1, κ Reactivity:Human QC Testing: Baboon or Cynomolgus or Rhesus Workshop: IV M047 Storage Buffer: Aqueous buffered solution containing BSA and ≤0.09% sodium azide PE Mouse Anti-Human CD11b Description:
Reacts with the 165 kDa adhesion glycoprotein (Mac-1, integrin αM subunit) which associates with the 95 kDa integrin β2 (CD18) to form the CD11b/CD18 complex. CD11b/Mac-1 is expressed on activated lymphocytes, monocytes, granulocytes, and a subset of NK cells. CD11b functions in cell-cell and cell-substrate interactions and as a receptor for iC3b, CD54 (ICAM-1), CD102 (ICAM-2) and CD50 (ICAM-3). This antibody significantly inhibits PMN aggregation in response to fMLP.
The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. The antibody was conjugated with R-PE under optimum conditions, and unconjugated antibody and free PE were removed by gel filtration chromatography. Store undiluted at 4° C and protected from prolonged exposure to light. Do not freeze.
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