PE Rat Anti-Mouse CD4

产品名称:PE 大鼠抗小鼠 CD4 抗体；PE Rat Anti-Mouse CD4

中文名称:PE 大鼠抗小鼠 CD4 抗体

英文名称:PE Rat Anti-Mouse CD4

PE Rat Anti-Mouse CD4 产品介绍：

Material Number: 557308
Alternate Name: Cd4; CD4 antigen; L3T4; Ly-4; T-cell surface antigen T4/Leu-3
Size: 0.1 mg
Concentration: 0.2 mg/ml
Clone: GK1.5
Immunogen: Mouse CTL clone V4
Isotype: Rat (LEW) IgG2b, κ
Reactivity: QC Testing: Mouse
Storage Buffer: Aqueous buffered solution containing ≤0.09% sodium azide



PE Rat Anti-Mouse CD4 Description：

The GK1.5 monoclonal antibody specifically binds to the mouse CD4 (L3T4) differentiation antigen. CD4 is expressed on most thymocytes, a 
subpopulation of mature T lymphocytes (i.e., MHC class II-restricted T cells, including most T helper cells), and a subset of NK-T cells. In 
addition, CD4 has also been reported to be detectable on pluripotent hematopoietic stem cells, bone marrow myeliod and B-lymphocyte 
precursors, intrathymic lymphoid precursors, and a subset of splenic dendritic cells. CD4 has also been reported to be expressed on the plasma 
membrane of mouse egg cells and is involved in adhesion of the egg to MHC class II-bearing sperm. CD4 is an antigen coreceptor on the 
T-cell surface which interacts with MHC class II molecules on antigen-presenting cells. It participates in T-cell activation through its 
association with the T-cell receptor complex and protein tyrosine kinase lck. GK1.5 mAb reportedly blocks binding of the RM4-5 (Cat. No. 
553046/553047) and H129.19 (Cat. No. 553650/553651), but not RM4-4 (Cat. No. 553055) antibodies. 

The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
The antibody was conjugated with R-PE under optimum conditions, and unconjugated antibody and free PE were removed.
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.