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PerCP Rat Anti-Mouse CD45

产品名称: PerCP Rat Anti-Mouse CD45
产品型号: BD-557235
产品展商: BD Pharmingen
产品文档: 无相关文档

简单介绍

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PerCP Rat Anti-Mouse CD45  的详细介绍

产品名称:PerCP Rat Anti-Mouse CD45 抗体;PerCP Rat Anti-Mouse CD45

中文名称:PerCP Rat Anti-Mouse CD45 抗体

英文名称:PerCP Rat Anti-Mouse CD45

PerCP Rat Anti-Mouse CD45 产品介绍:

Material Number: 557235
Alternate Name: Leukocyte Common Antigen (LCA), Ly-5, T200
Size: 0.1 mg
Concentration: 0.2 mg/ml
Clone: 30-F11
Immunogen: Mouse Thymus / Spleen
Isotype: Rat (LOU) IgG2b, κ
Reactivity: QC Testing: Mouse
Storage Buffer: Aqueous buffered solution containing ≤0.09% sodium azide.


PerCP Rat Anti-Mouse CD45 Description:

The 30-F11 clone has been reported to react with all isoforms and both alloantigens of CD45, which is found on hematopoietic stem cells and
all cells of hematopoietic origin, except erythrocytes. CD45 is a transmembrane glycoprotein which is expressed at high levels on the
cell-surface, and its presence distinguishes leukocytes from non-hematopoietic cells. CD45 is a member of the Protein Tyrosine Phosphatase
(PTP) family, where the intracellular carboxy-terminal region contains two PTP catalytic domains, and the extracellular region is highly
variable due to alternative splicing of exons 4, 5, and 6 (designated as A, B, and C, respectively). CD45 isoforms play complex roles in T-cell
and B-cell antigen receptor signal transduction and the CD45 isoforms detected in the mouse are cell type-, maturation-, and activation
state-specific


PerCP Rat Anti-Mouse CD45 Preparation and Storage:

The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
The antibody was conjugated with PerCP under optimum conditions, and unconjugated antibody and free PerCP were removed. Storage
of PerCP conjugates in unoptimized diluent is not recommended and may result in loss of signal intensity.
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.



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