产品名称:PE 小鼠抗人 CD80 抗体;PE Mouse Anti-Human CD80
中文名称:PE 小鼠抗人 CD80 抗体
英文名称:PE Mouse Anti-Human CD80
PE Mouse Anti-Human CD80 产品介绍:
Material Number: 557227 Alternate Name: B7-1 Size: 100 tests Vol. per Test: 20 µl Clone: L307.4 Isotype: Mouse IgG1, κ Reactivity: QC Testing: Human Workshop: V B7.5 Storage Buffer: Aqueous buffered solution containing BSA and ≤0.09% sodium azide. PE Mouse Anti-Human CD80 Description:
Reacts with B7/BB1, a 60 kDa transmembrane glycoprotein which was clustered as CD80 in the Fifth International Workshop on Human Leukocyte Differentiation Antigens. CD80, a member of the Ig supergene family, is expressed on activated B cells, macrophages, and dendritic cells. It is the ligand for two molecules expressed on T cells, CD28 and CD152 (CTLA-4). CD80 is also expressed on activated CD4+ and CD8+ T cells, appearing late after activation suggesting that activated T cells may be capable of autocrine costimulation via the CD28 activation pathway. The binding of CD28 by anti-CD28 or by CD80 results in T-cell activation and a signal for IL-2 production.
The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. The antibody was conjugated with R-PE under optimum conditions, and unconjugated antibody and free PE were removed. Store undiluted at 4° C and protected from prolonged exposure to light. Do not freeze.
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