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PE Mouse Anti-Human CD80

产品名称: PE Mouse Anti-Human CD80
产品型号: BD-557227
产品展商: BD Pharmingen
产品文档: 无相关文档

简单介绍

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PE Mouse Anti-Human CD80  的详细介绍

产品名称:PE 小鼠抗人 CD80 抗体;PE Mouse Anti-Human CD80

中文名称:PE 小鼠抗人 CD80 抗体

英文名称:PE Mouse Anti-Human CD80

PE Mouse Anti-Human CD80 产品介绍:

Material Number: 557227
Alternate Name: B7-1
Size: 100 tests
Vol. per Test: 20 µl
Clone: L307.4
Isotype: Mouse IgG1, κ
Reactivity: QC Testing: Human
Workshop: V B7.5
Storage Buffer: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

PE Mouse Anti-Human CD80 Description:

Reacts with B7/BB1, a 60 kDa transmembrane glycoprotein which was clustered as CD80 in the Fifth International Workshop on Human
Leukocyte Differentiation Antigens. CD80, a member of the Ig supergene family, is expressed on activated B cells, macrophages, and
dendritic cells. It is the ligand for two molecules expressed on T cells, CD28 and CD152 (CTLA-4). CD80 is also expressed on activated
CD4+ and CD8+ T cells, appearing late after activation suggesting that activated T cells may be capable of autocrine costimulation via the
CD28 activation pathway. The binding of CD28 by anti-CD28 or by CD80 results in T-cell activation and a signal for IL-2 production.


PE Mouse Anti-Human CD80 Preparation and Storage:

The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
The antibody was conjugated with R-PE under optimum conditions, and unconjugated antibody and free PE were removed.
Store undiluted at 4° C and protected from prolonged exposure to light. Do not freeze.



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