产品名称:PE 小鼠抗人 CD25 抗体;PE Mouse Anti-Human CD25
中文名称:PE 小鼠抗人 CD25 抗体
英文名称:PE Mouse Anti-Human CD25
PE Mouse Anti-Human CD25 产品介绍:
Material Number: 557138 Alternate Name: IL-2R; IL2RA; IL-2Rα; TCGFR; TAC antigen; p55 Size: 50 tests Vol. per Test: 20 µl Clone: M-A251 Isotype: Mouse IgG1, κ Reactivity: Human QC Testing: Baboon or Rhesus or Cynomolgus Workshop: IV A053 Storage Buffer: Aqueous buffered solution containing BSA and ≤0.09% sodium azide. PE Mouse Anti-Human CD25 Description:
The M-A251 monoclonal antibody specifically binds to the 55 kDa type I transmembrane glycoprotein known as the low-affinity interleukin-2 receptor alpha chain subunit (IL-2Rα). CD25 is expressed on regulatory T cells and on activated lymphocytes (T and B) and monocytes. It associates with the IL-2Rβ/CD122 and the IL-2Rγ/CD132 receptor chains to form the high-affinity IL-2R complex. CD25 expression on T and B lymphocytes is upregulated by antigenic or mitogenic stimulation. Soluble CD25/IL-2Rα is produced as a consequence of lymphocyte stimulation and is found in biological fluids following inflammatory responses.
The antibody was conjugated with R-PE under optimum conditions, and unconjugated antibody and free PE were removed. The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
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