Purified Mouse Anti-Cytochrome C

产品名称:Purified Mouse Anti-Cytochrome C

Purified Mouse Anti-Cytochrome C 产品介绍：

Material Number: 556433
Size: 0.1 mg
Concentration: 0.5 mg/ml
Clone: 7H8.2C12
Immunogen: Synthetic Peptides of Pigeon Cytochrome C
Isotype: Mouse IgG2b, κ
Reactivity:QC Testing: Human
Tested in Development: Mouse, Rat, Horse, Pigeon
Storage Buffer: Aqueous buffered solution containing ≤0.09% sodium azide

Purified Mouse Anti-Cytochrome C Description：

A cytochrome is an electron-transporting protein that contains a heme prosthetic group. Cytochromes have been known to be essential
components of the mitochondrial respiratory chain since 1925. The iron atom of the heme group in cytochromes alternates between a reduced
ferrous (+2) state and an oxidized ferric (+3) state during electron transport in oxidative phosphorylation. Cytochromes are classified into four
groups (a, b, c, and d) according to spectrochemical characteristics, and there are five cytochromes between Coenzyme QH2 and O2 in the
electron transport chain. Cytochrome c is a water-soluble peripheral membrane protein of the mitochondria and transports electrons from the
Coenzyme QH2 - Cytochrome c reductase complex to the Cytochrome c oxidase complex. Recently it has been suggested that Cytochrome c
may be required for cells to undergo apoptosis. Mitochondria may be involved in apoptosis by releasing Cytochrome c to the cytosol where it
functions in the activation of Caspase 3 (CPP32), an ICE family molecule that has been shown to trigger apoptosis when activated. In the
cytoplasm Cytochrome C might exist in polymeric forms, appearing as a 58-60 kDa band by western blot analysis, rather than the monomeric
form. Monomeric Cytochrome c migrates at a reduced molecular weight of 15 kDa.

The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
Store undiluted at 4° C.

Purified Mouse Anti-Cytochrome C Suggested Companion Products：

Catalog Number Name Size Clone
556432 Purified Mouse Anti-Cytochrome c 0.1 mg 6H2.B4