PE Mouse Anti-Human CD29

产品名称:PE 小鼠抗人 CD29 抗体；PE Mouse Anti-Human CD29

中文名称:PE 小鼠抗人 CD29 抗体

英文名称:PE Mouse Anti-Human CD29

PE Mouse Anti-Human CD29 产品介绍：

Material Number: 556049
Alternate Name: Integrin β1 Chain
Size: 100 tests
Vol. per Test: 20 µl
Clone: HUTS-21
Isotype: Mouse IgG2a, κ
Reactivity: QC Testing: Human
Workshop: NA
Storage Buffer: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.


PE Mouse Anti-Human CD29 Description：

Reacts with the 130 kDa integrin β1 subunit, CD29, that is expressed following cell activation as a heterodimeric complex with one of nine
distinct α subunits, comprising the very late activation antigen (VLA) subfamily of adhesion receptors. The HUTS-21 β1 epitope is weakly
expressed on resting lymphocytes, but is upregulated by TPA, Ca++ ionophore, or another CD29 antibody, TS2/16. This upregulation is
Mn++ dependent and not supported by other divalent cations such as Ca++ and/or Mg++. The VLA receptors have a broad cellular
distribution and interact with ligands like VCAm-1 and MAdCAM-1 during cell adhesion. They also interact with extra-cellular matrices
including collagen, laminin, fibronectin and others. HUTS-21 antibody enhances adherence of TPA-activated lymphocytes to fibronectin.

The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
The antibody was conjugated with R-PE under optimum conditions, and unconjugated antibody and free PE were removed.
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.