产品名称:PE 小鼠抗人 CD47 抗体;PE Mouse Anti-Human CD47
中文名称:PE 小鼠抗人 CD47 抗体
英文名称:PE Mouse Anti-Human CD47
PE Mouse Anti-Human CD47 产品介绍:
Material Number: 556046 Alternate Name: IAP Size: 100 tests Vol. per Test: 20 µl Clone: B6H12 Isotype: Mouse IgG1, κ Reactivity: QC Testing: Human Workshop: BP400/V S271 Storage Buffer: Aqueous buffered solution containing BSA and ≤0.09% sodium azide
PE Mouse Anti-Human CD47 Description:
Reacts with a 42-52 kD N-linked glycan protein. CD47 antigen, also known as integrin-associated protein (IAP), is expressed on all hematopoietic cells, including leukocytes, platelets and erythrocytes. It is also expressed on epithelial cells, endothelial cells, fibroblasts and many tumor cell lines. CD47 may play a role as a signal transducer in the regulation of cation fluxes across cell membranes and in the chemotactic and adhesive interactions of leukocytes with endothelial cells. B6H12 antibody is capable of blocking phagocytosis of microparticles by peripheral blood granulocytes. It has also been reported to induce proliferation of CD3-activated T cells.
The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. The antibody was conjugated with R-PE under optimum conditions, and unconjugated antibody and free PE were removed by gel filtration chromatography. Store undiluted at 4° C and protected from prolonged exposure to light. Do not freeze.
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