产品名称:PE 小鼠抗人 CD163 抗体;PE Mouse Anti-Human CD163
中文名称:PE 小鼠抗人 CD163 抗体
英文名称:PE Mouse Anti-Human CD163
PE Mouse Anti-Human CD163 产品介绍:
Material Number: 556018 Size: 100 tests Vol. per Test: 20 µl Clone: GHI/61 Isotype: Mouse IgG1, κ Reactivity: QC Testing: Human Workshop: VI M38 Storage Buffer: Aqueous buffered solution containing BSA and ≤0.09% sodium azide. PE Mouse Anti-Human CD163 Description:
The GHI/61 monoclonal antibody specifically binds to human CD163. CD163 is also known as Scavenger receptor cysteine-rich type 1 protein M130 (M130), Hemoglobin scavenger receptor and Macrophage-associated antigen. CD163 is a 110-130 kDa transmembrane glycoprotein. CD163 is a monocyte/macrophage-restricted antigen expressed on the majority of tissue macrophages and peripheral blood monocytes. CD163 belongs to the scavenger receptor superfamily. Its expression on monocytes is upregulated upon cellular activation. CD163 expression reportedly changes on monocytes and macrophages as these cells differentiate. This finding suggests a role for this molecule in the differentiation and/or regulation of monocyte and macrophage function. CD163 may play a role in the clearance and endocytosis of hemoglobin and haptoglobin complexes by macrophages.
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. The antibody was conjugated with R-PE under optimum conditions, and unconjugated antibody and free PE were removed.
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