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PE Mouse Anti-Human CD163

产品名称: PE Mouse Anti-Human CD163
产品型号: BD-556018
产品展商: BD Pharmingen
产品文档: 无相关文档

简单介绍

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PE Mouse Anti-Human CD163  的详细介绍

产品名称:PE 小鼠抗人 CD163 抗体;PE Mouse Anti-Human CD163

中文名称:PE 小鼠抗人 CD163 抗体

英文名称:PE Mouse Anti-Human CD163

PE Mouse Anti-Human CD163 产品介绍:

Material Number: 556018
Size: 100 tests
Vol. per Test: 20 µl
Clone: GHI/61
Isotype: Mouse IgG1, κ
Reactivity: QC Testing: Human
Workshop: VI M38
Storage Buffer: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

PE Mouse Anti-Human CD163 Description:

The GHI/61 monoclonal antibody specifically binds to human CD163. CD163 is also known as Scavenger receptor cysteine-rich type 1
protein M130 (M130), Hemoglobin scavenger receptor and Macrophage-associated antigen. CD163 is a 110-130 kDa transmembrane
glycoprotein. CD163 is a monocyte/macrophage-restricted antigen expressed on the majority of tissue macrophages and peripheral blood
monocytes. CD163 belongs to the scavenger receptor superfamily. Its expression on monocytes is upregulated upon cellular activation. CD163
expression reportedly changes on monocytes and macrophages as these cells differentiate. This finding suggests a role for this molecule in the
differentiation and/or regulation of monocyte and macrophage function. CD163 may play a role in the clearance and endocytosis of
hemoglobin and haptoglobin complexes by macrophages.


PE Mouse Anti-Human CD163 Preparation and Storage:

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
The antibody was conjugated with R-PE under optimum conditions, and unconjugated antibody and free PE were removed.



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