产品名称:PE 小鼠抗人 CD221 抗体;PE Mouse Anti-Human CD221
中文名称:PE 小鼠抗人 CD221 抗体
英文名称:PE Mouse Anti-Human CD221
PE Mouse Anti-Human CD221 产品介绍:
Material Number: 555999 Alternate Name: IGF-I Receptor α Size: 100 tests Vol. per Test: 20 µl Clone: 1H7 Isotype: Mouse IgG1, κ Reactivity: QC Testing: Human Storage Buffer: Aqueous buffered solution containing BSA and ≤0.09% sodium azide. PE Mouse Anti-Human CD221 Description:
Reacts with human insulin-like growth factor-I (IGF-I) receptor α subunit (135 kDa). IGF-IRα is a glycoprotein complex composed of two extracellular α subunits and two transmembrane β subunits. The transmembrane subunits play a role in tyrosine phosphorylation of several intracellular signaling proteins. IGF-IRα is structurally and functionally similar to insulin receptor and is expressed on a variety of human hematopoietic and non-hematopoietic cells. It mediates the effects of IGF-I and IGF-II on cellular growth. 1H7 does not cross react with human insulin receptor and it can block IGF-I or IGF-II stimulated cell growth.
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. The antibody was conjugated with R-PE under optimum conditions, and unconjugated antibody and free PE were removed.
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