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PE Mouse Anti-Human CD221

产品名称: PE Mouse Anti-Human CD221
产品型号: BD-555999
产品展商: BD Pharmingen
产品文档: 无相关文档

简单介绍

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PE Mouse Anti-Human CD221  的详细介绍

产品名称:PE 小鼠抗人 CD221 抗体;PE Mouse Anti-Human CD221

中文名称:PE 小鼠抗人 CD221 抗体

英文名称:PE Mouse Anti-Human CD221

PE Mouse Anti-Human CD221 产品介绍:

Material Number: 555999
Alternate Name: IGF-I Receptor α
Size: 100 tests
Vol. per Test: 20 µl
Clone: 1H7
Isotype: Mouse IgG1, κ
Reactivity: QC Testing: Human
Storage Buffer: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

PE Mouse Anti-Human CD221 Description:

Reacts with human insulin-like growth factor-I (IGF-I) receptor α subunit (135 kDa). IGF-IRα is a glycoprotein complex composed of two
extracellular α subunits and two transmembrane β subunits. The transmembrane subunits play a role in tyrosine phosphorylation of several
intracellular signaling proteins. IGF-IRα is structurally and functionally similar to insulin receptor and is expressed on a variety of human
hematopoietic and non-hematopoietic cells. It mediates the effects of IGF-I and IGF-II on cellular growth. 1H7 does not cross react with
human insulin receptor and it can block IGF-I or IGF-II stimulated cell growth.


PE Mouse Anti-Human CD221 Preparation and Storage:

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
The antibody was conjugated with R-PE under optimum conditions, and unconjugated antibody and free PE were removed.



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