APC Mouse Anti-Human CD184

产品名称:APC 小鼠抗人 CD184 抗体；APC Mouse Anti-Human CD184

中文名称:APC 小鼠抗人 CD184 抗体

英文名称:APC Mouse Anti-Human CD184

APC Mouse Anti-Human CD184 产品介绍：

Material Number: 555976
Alternate Name: CXCR4; Fusin; SDF-1 receptor; LAP3; LCR1; LESTR; NPYY3R; NPY3R; WHIM; HM89
Size: 100 tests
Vol. per Test: 20 µl
Clone: 12G5
Isotype: Mouse (BALB/c) IgG2a, κ
Reactivity: QC Testing: Human
Workshop: VII 70204, 70305
Storage Buffer: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.


APC Mouse Anti-Human CD184 Description：

The 12G5 monoclonal antibody specifically binds to CD184, also known as CXCR4 and Fusin. CD184/CXCR4 is a seven-transmembrane
domain, G-protein-linked, glycoprotein chemokine receptor. CD184 serves as a receptor for the C-X-C chemokine, SDF-1. It is expressed on a
wide variety of hematopietic cells, vascular endothelial cells and cells of the nervous system. CD184 plays a variety of roles in hematopoiesis,
vascularization and neural development. CD184 also functions as a coreceptor for infection with T-cell tropic strains of HIV-1 and as a
receptor for CD4-independent infection by some HIV isolates. The 12G5 antibody has been reported to block CD4-independent infection by
HIV-2 and CD4-dependent infection by some T-cell tropic isolates of HIV-1.

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
The antibody was conjugated to APC under optimum conditions, and unconjugated antibody and free APC were removed.