产品名称:FITC 小鼠抗人 NKB1 抗体;FITC Mouse Anti-Human NKB1
中文名称:FITC 小鼠抗人 NKB1 抗体
英文名称:FITC Mouse Anti-Human NKB1
FITC Mouse Anti-Human NKB1 产品介绍:
Material Number: 555966 Alternate Name: KIR Size: 100 tests Vol. per Test: 20 µl Clone: DX9 Isotype: Mouse IgG1, κ Reactivity: QC Testing: Human Storage Buffer: Aqueous buffered solution containing BSA and ≤0.09% sodium azide FITC Mouse Anti-Human NKB1 Description:
Reacts with the killer cell inhibitory receptor (KIR), NKB1, a 70 kDa glycoprotein, member of the Ig superfamily, expressed on a subset of natural killer cells and a small subset of T cells. Expression of NKB1 has been observed to vary among individuals. KIR molecules specifically recognize a certain group of HLA class I antigens. Interaction of NKB1 with specific HLA-B antigen on a target cell inhibits cell mediated cytotxicity, possibly by delivering a negative signal preventing lymphocyte activation. It is suggested that this MHC class I-KIR interaction works as a regulatory mechanism of NK and T-cell responses to antigenic challenge
The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. The antibody was conjugated with FITC under optimum conditions, and unreacted FITC was removed. Store undiluted at 4° C and protected from prolonged exposure to light. Do not freeze.
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