产品名称:PE 小鼠抗人 CD137 抗体;PE Mouse Anti-Human CD137
中文名称:PE 小鼠抗人 CD137 抗体
英文名称:PE Mouse Anti-Human CD137
PE Mouse Anti-Human CD137 产品介绍:
Material Number: 555956 Alternate Name: 4-1BB Size: 100 tests Vol. per Test: 20 µl Clone: 4B4-1 Isotype: Mouse IgG1, κ Reactivity: QC Testing: Human Workshop: VI C-7 Storage Buffer: Aqueous buffered solution containing BSA and ≤0.09% sodium azide. PE Mouse Anti-Human CD137 Description:
Reacts with 4-1BB, a 30 kDa glycoprotein expressed on activated T cells. 4-1BB can be detected on Con A or PHA-stimulated peripheral blood T cells (CD4+ and CD8+) and on CEM cells (human T-cell leukemia) following 2 day PMA and ionomycin stimulation, but not on resting T cells. 4-1BB is reported to be a participant in T-cell activation, being responsible for rescuing T cells from activation-induced apoptosis, upregulation of Th1-type, T-helper cells, downregulation of Th2-type cytokine production, and induction of cell adhesion to fibronectin.
The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. The antibody was conjugated with R-PE under optimum conditions, and unconjugated antibody and free PE were removed. Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
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