产品名称:FITC 小鼠抗人 CD58 抗体;FITC Mouse Anti-Human CD58
中文名称:FITC 小鼠抗人 CD58 抗体
英文名称:FITC Mouse Anti-Human CD58
FITC Mouse Anti-Human CD58 产品介绍:
Material Number: 555920 Alternate Name: LFA-3 Size: 100 tests Vol. per Test: 20 µl Clone: 1C3 (AICD58.6) Isotype: Mouse IgG2a κ Reactivity:QC Testing: Human Tested in Development: Dog
Workshop: V S029 Storage Buffer: Aqueous buffered solution containing BSA and ≤0.09% sodium azide. FITC Mouse Anti-Human CD58 Description:
Reacts with a 60-70 kDa membrane glycoprotein member of the immunoglobulin superfamily. CD58, also referred to as the lymphocyte function-associated antigen-3 (LFA-3), has a wide tissue distribution, being expressed on both hematopoietic and non-hematopoietic cells, including endothelial cells and fibroblasts. There are two isoforms of CD58: a glycosylphosphatidylinositol (GPI)-linked formed and a transmembrane form. Both isoforms may be expressed in the same cell type. Erythrocytes, however, only have the GPI-linked isoform. CD58 interacts with CD2 during cell adhesion. This binding can enhance antigen-specific T-cell activation.
The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. The antibody was conjugated with FITC under optimum conditions, and unreacted FITC was removed. Store undiluted at 4° C and protected from prolonged exposure to light. Do not freeze.
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