APC Mouse Anti-Human CD152

产品名称:APC  小鼠抗人 CD152 抗体；APC Mouse Anti-Human CD152

中文名称:APC  小鼠抗人 CD152 抗体

英文名称:APC Mouse Anti-Human CD152

APC Mouse Anti-Human CD152 产品介绍：

Material Number: 555855
Alternate Name: CTLA-4
Size: 100 tests
Vol. per Test: 20 µl
Clone: BNI3
Isotype: Mouse IgG2a, κ
Reactivity: QC Testing: Human
Workshop: NA
Storage Buffer: Aqueous buffered solution containing BSA and ≤0.09% sodium azide



APC Mouse Anti-Human CD152 Description：

Reacts with the "cytolytic T lymphocyte-associated antigen", CTLA-4. CTLA-4 is transiently expressed on activated CD28+ T cells and binds 
to CD80 and CD86 present on antigen presenting cells (APC) with high avidity. This interaction appears to deliver a negative regulatory 
signal to the T cell. There are recent reports that indicate that CTLA-4 is also expressed on B cells when cultured with activated T cells, 
suggesting a possible role of CTLA-4 in the regulation of B-cell response. Immobilized BNI3.1 enhances T-cell proliferation induced by CD3 
and CD28. 

The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
The antibody was conjugated to APC under optimum conditions, and unconjugated antibody and free APC were removed.
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.