PE Mouse Anti-Human CD152

产品名称:PE 小鼠抗人 CD152 抗体；PE Mouse Anti-Human CD152

中文名称:PE 小鼠抗人 CD152 抗体

英文名称:PE Mouse Anti-Human CD152

PE Mouse Anti-Human CD152 产品介绍：

Material Number: 555853
Alternate Name: CTLA-4
Size: 100 tests
Vol. per Test: 20 µl
Clone: BNI3
Isotype: Mouse IgG2a, κ
Reactivity: QC Testing: Human
Workshop: NA
Storage Buffer: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.


PE Mouse Anti-Human CD152 Description：

Reacts with the "cytolytic T lymphocyte-associated antigen", CTLA-4. CTLA-4 is transiently expressed on activated CD28+ T cells and binds 
to CD80 and CD86 present on antigen presenting cells (APC) with high avidity. This interaction appears to deliver a negative regulatory 
signal to the T cell. There are recent reports that indicate that CTLA-4 is also expressed on B cells when cultured with activated T cells, 
suggesting a possible role of CTLA-4 in the regulation of B-cell response. Immobilized BNI3.1 enhances T-cell proliferation induced by CD3 
and CD28.

The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
The antibody was conjugated with R-PE under optimum conditions, and unconjugated antibody and free PE were removed.
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.