产品名称:PE 小鼠抗人 CD61 抗体;PE Mouse Anti-Human CD61
中文名称:PE 小鼠抗人 CD61 抗体
英文名称:PE Mouse Anti-Human CD61
PE Mouse Anti-Human CD61 产品介绍:
Material Number: 555754 Alternate Name: Integrin β3 Chain Size: 100 tests Vol. per Test: 20 µl Clone: VI-PL2 Isotype: Mouse IgG1, κ Reactivity: QC Testing: Human Tested in Development: Baboon, Rhesus, Cynomolgus, Bovine. Workshop: V 5T-124 Storage Buffer: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Reacts with integrin β3, a 105 kDa transmembrane glycoprotein, expressed on platelets, megakaryocytes, osteoclasts and endothelia. Integrin β3 associates with gpIIa (CD41) to form the CD41/CD61 complex which mediates platelet adhesion and aggregation. CD61 also associates with CD51 to form the CD51/CD61 complex (vitronectin receptor). CD61 appears to bind to fibrinogen, fibronectin, vWF, vitronectin, and thrombospondin to mediate cell adhesion.
The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. The antibody was conjugated with R-PE under optimum conditions, and unconjugated antibody and free PE were removed. Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
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