产品名称:PE 小鼠抗人 CD23 抗体;PE Mouse Anti-Human CD23
中文名称:PE 小鼠抗人 CD23 抗体
英文名称:PE Mouse Anti-Human CD23
PE Mouse Anti-Human CD23 产品介绍:
Material Number: 555711 Size: 100 tests Vol. per Test: 20 µl Clone: M-L233 Isotype: Mouse IgG1, κ Reactivity: QC Testing: Human Workshop: V CD23.15 Storage Buffer: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
The M-L233 antibody reacts with the low affinity receptor for human IgE, FcεRII/CD23. CD23 is a type II membrane protein which can be expressed by B cells, monocytes, macrophages, eosinophils, platelets, and dendritic cells. CD23 can mediate IgE-dependent cytotoxicity and phagocytosis by macrophages and eosinophils. Soluble CD23 (sCD23) can be released by CD23+ cells as a result of proteolytic cleavage of membrane CD23. Larger fragments of sCD23 (e.g., 37-25 kDa) retain their IgE-binding capacity whereas smaller fragments (i.e., ≤ 12 kDa) do not. Soluble CD23 may have immunoregulatory effects on the growth and differentiation of B cells and other cell types.
The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. The antibody was conjugated with R-PE under optimum conditions, and unconjugated antibody and free PE were removed. Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
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