Purified NA/LE Mouse Anti-Human CD95

产品名称:Purified NA/LE 小鼠抗人 CD95 抗体；Purified NA/LE Mouse Anti-Human CD95

中文名称:Purified NA/LE 小鼠抗人 CD95 抗体

英文名称:Purified NA/LE Mouse Anti-Human CD95

Purified NA/LE Mouse Anti-Human CD95 产品介绍：

Material Number: 555670
Alternate Name: APO-1; FAS; TNFRSF6; APT1; ALPS1A; FAS1; FASTM; FASLG receptor
Size: 0.5 mg
Concentration: 1.0 mg/ml
Clone: DX2
Immunogen: Human CD95-transfected L ceils
Isotype: Mouse (C3H) IgG1, κ
Reactivity: QC Testing: Human
Tested in Development: Rhesus, Cynomolgus, Baboon, Pig, Dog
Workshop: VI C-64
Storage Buffer: No azide/low endotoxin: Aqueous buffered solution containing no preservative, 
0.2µm sterile filtered. Endotoxin level is ≤0.01 EU/µg (≤0.001 ng/µg) of 
protein as determined by the LAL assay.



Purified NA/LE Mouse Anti-Human CD95 Description：

The DX2 monoclonal antibody specifically binds to the human Fas antigen (also called APO-1). This 45 kDa transmembrane cell surface 
molecule was designated as CD95 at the Fifth HLDA Workshop. Fas is a member of the TNF-receptor superfamily and is also known as 
Tumor necrosis factor receptor superfamily member 6 (TNFRSF6). It is expressed on a variety of normal and neoplastic cells including 
activated T and B lymphocytes and some undifferentiated thymocytes. The Fas/CD95 antigen is a polypeptide that plays a role in the 
programmed sequence of events leading to cell death, termed apoptosis. The DX2 clone specifically reacts with murine L cells, murine L1210 
leukemia cells and murine P815 mastocytoma cells transfected with human Fas cDNA but not with untransfected parental cell lines. 
Crosslinking CD95 with DX2 antibody delivers an apoptotic signal indicating that DX2 recognizes a functional epitope of the CD95 antigen. 

Store undiluted at 4°C.
The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
This preparation contains no preservatives, thus it should be handled under aseptic conditions.