产品名称:APC 小鼠抗人 CD40 抗体;APC Mouse Anti-Human CD40
中文名称:APC 小鼠抗人 CD40 抗体
英文名称:APC Mouse Anti-Human CD40
APC Mouse Anti-Human CD40 产品介绍:
Material Number: 555591 Size: 100 tests Vol. per Test: 20 µl Clone: 5C3 Isotype: Mouse IgG1 κ Reactivity: QC Testing: Human Workshop: V CD40.4 Storage Buffer: Aqueous buffered solution containing BSA and ≤0.09% sodium azide APC Mouse Anti-Human CD40 Description:
This antibody reacts with a 45-48 kDa type I integral membrane glycoprotein present on peripheral blood and tonsillar B cells, but not expressed on terminally differentiated B cells. CD40 is also present on some epithelial cells, carcinomas and lymphoid dendritic cells. This antibody is useful for studies of B-cell growth and function. Anti-CD40 antibodies have been reported to stimulated B-cell proliferation when costimulated with anti-µ, anti-CD20 antibodies or with phorbol esters. 5C3 is capable of inducing B-cell proliferation when presented with IL-4.
The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. The antibody was conjugated to APC under optimum conditions, and unconjugated antibody and free APC were removed by gel filtration chromatography. Store undiluted at 4° C and protected from prolonged exposure to light. Do not freeze.
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