产品名称:PE 小鼠抗人 CD45RO 抗体;PE Mouse Anti-Human CD45RO
中文名称:PE 小鼠抗人 CD45RO 抗体
英文名称:PE Mouse Anti-Human CD45RO
PE Mouse Anti-Human CD45RO 产品介绍:
Material Number: 555493 Size: 100 tests Vol. per Test: 20 µl Clone: UCHL1 Isotype: Mouse (BALB/c) IgG2a, κ Reactivity: QC Testing: Human Workshop: IV N31 Storage Buffer: Aqueous buffered solution containing BSA and ≤0.09% sodium azide. PE Mouse Anti-Human CD45RO Description:
The UCHL1 monoclonal antibody specifically reacts with the 180 kDa isoform of CD45 (aka, the Leukocyte Common Antigen). CD45RO is a type I transmembrane glycoprotein that has cytoplasmic protein tyrosine phosphatase activity and functions in signal transduction pathways. This CD45 isoform does not include amino acid sequences encoded by the variable CD45 exons A, B, or C. CD45RO is expressed on most thymocytes, activated T cells, memory T cells, granulocytes and monocytes, but only on a proportion of resting T cells. CD45RO and CD45RA antibodies seem to define complementary, predominantly non-overlapping, populations in resting peripheral T cells, demonstrating heterogeneity within the CD8 and CD4 subpopulations. CD45RO binds to CD22.
The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. The antibody was conjugated with R-PE under optimum conditions, and unconjugated antibody and free PE were removed. Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
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