产品名称:FITC 小鼠抗人 CD42b 抗体;FITC Mouse Anti-Human CD42b
中文名称:FITC 小鼠抗人 CD42b 抗体
英文名称:FITC Mouse Anti-Human CD42b
FITC Mouse Anti-Human CD42b 产品介绍:
Material Number: 555472 Alternate Name: GP1BA; GPIbalpha; GP-Ib alpha; GPIb-alpha; CD42b-alpha; Glycocalicin; BSS Size: 100 tests Vol. per Test: 20 µl Clone: HIP1 Isotype: Mouse IgG1, κ Reactivity: QC Testing: Human Workshop: IV P40 Storage Buffer: Aqueous buffered solution containing BSA and ≤0.09% sodium azide. FITC Mouse Anti-Human CD42b Description:
The HIP1 monoclonal antibody specifically binds to CD42b. CD42b is also known as the Platelet glycoprotein Ib alpha chain that is encoded by the GP1BA gene. CD42b is disulfide bonded to CD42c to form a 170 kDa heterodimer, GPIb. GPIb forms a noncovalent complex with CD42a and CD42d (CD42 complex) that is expressed on platelets and megakaryocytes. The CD42 complex serves as the von Willebrand Factor (vWF) surface receptor involved in the adhesion of platelets to the subendothelium of damaged vascular walls. HIP1 inhibits the ristocetin-dependent binding of vWF to platelets and partially inhibits collagen-induced aggregation.
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. The antibody was conjugated with FITC under optimum conditions, and unreacted FITC was removed.
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