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Purified Mouse Anti-Human CD42b

产品名称: Purified Mouse Anti-Human CD42b
产品型号: BD-555471
产品展商: BD Pharmingen
产品文档: 无相关文档

简单介绍

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Purified Mouse Anti-Human CD42b  的详细介绍

产品名称:Purified 小鼠抗人 CD42b 抗体;Purified Mouse Anti-Human CD42b

中文名称:Purified 小鼠抗人 CD42b 抗体

英文名称:Purified Mouse Anti-Human CD42b

Purified Mouse Anti-Human CD42b 产品介绍:

Material Number: 555471
Size: 0.1 mg
Concentration: 0.5 mg/ml
Clone: HIP1
Isotype: Mouse IgG1, κ
Reactivity: QC Testing: Human
Workshop: IV P40
Storage Buffer: Aqueous buffered solution containing ≤0.09% sodium azide.

Purified Mouse Anti-Human CD42b Description:

The HIP1 monoclonal antibody specifically binds to CD42b. CD42b is also known as the Platelet glycoprotein Ib alpha chain that is encoded
by the GP1BA gene. CD42b is disulfide bonded to CD42c to form a 170 kDa heterodimer, GPIb. GPIb forms a noncovalent complex with
CD42a and CD42d (CD42 complex) that is expressed on platelets and megakaryocytes. The CD42 complex serves as the von Willebrand
Factor (vWF) surface receptor involved in the adhesion of platelets to the subendothelium of damaged vascular walls. HIP1 inhibits the
ristocetin-dependent binding of vWF to platelets and partially inhibits collagen-induced aggregation.



Purified Mouse Anti-Human CD42b Preparation and Storage:

Store undiluted at 4°C.
The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.



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