PE Mouse anti-Human CD39

产品名称:PE 小鼠抗人 抗体；PE Mouse anti-Human CD39

中文名称:PE 小鼠抗人 抗体

英文名称:PE Mouse anti-Human CD39

PE Mouse anti-Human CD39 产品介绍：

Material Number: 555464
Alternate Name: ENTPD1, NTPDase 1
Size: 100 tests
Vol. per Test: 20 µl
Clone: TU66
Isotype: Mouse IgG2b, κ
Reactivity: QC Testing: Human
Storage Buffer: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

PE Mouse anti-Human CD39 Description：

The TU66 monoclonal antibody reacts with human CD39 also known as ectonucleoside triphosphate diphosphohydrolase 1 (ENTPD1) an
ectoenzyme that degrades ATP to AMP. It is a member of the family of ectonucleoside triphosphate dihydrolases (E-NTPDases) known to be
involved in regulation of extracellular nucleotide catabolism, controlling the extracellular nucleoside triphosphate pool (NTP). CD39 is
expressed on a subset of T cells, B cells and dendritic cells with weak staining of monocytes and granulocytes. Recently, CD39 has been
found to be expressed primarly by immune-suppressive Foxp3(+) regulatory T (Treg) cells in both human and mice. In humans, CD39 is
restricted to a subset of Foxp3(+) regulatory effector/memory-like T cells. In mice, the enzyme is present on most if not all CD4(+)CD25(+)
cells and CD39 expression is driven by Foxp3. It is thought that CD39 allows Treg cells to enter inflamed areas where high levels of ATP are
present.

The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
The antibody was conjugated with R-PE under optimum conditions, and unconjugated antibody and free PE were removed.
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.