产品名称:PE 小鼠抗人 CD38 抗体;PE Mouse Anti-Human CD38
中文名称:PE 小鼠抗人 CD38 抗体
英文名称:PE Mouse Anti-Human CD38
PE Mouse Anti-Human CD38 产品介绍:
Material Number: 555460 Size: 100 tests Vol. per Test: 20 µl Clone: HIT2 Isotype: Mouse IgG1, κ Reactivity: QC Testing: Human Workshop: III 155 Storage Buffer: Aqueous buffered solution containing BSA and ≤0.09% sodium azide PE Mouse Anti-Human CD38 Description:
The HIT2 monoclonal antibody specifically binds to CD38. CD38 is a 45 kDa type II single-chain transmembrane glycoprotein present on thymocytes, activated T cells and terminally differentiated B cells (plasma cells). Other reactive cells include monocytes, macrophages, dendritic cells and some epithelial cells. The CD38 antigen acts as an ectoenzyme that catalyzes the synthesis and hydrolysis of a Ca++ mobilizing agent, cyclic ADP-ribose. This intracellular calcium plays an important role in cell signalling pathways. Reports describe CD38 as participating in adhesion with CD31, immunoregulatory functions involving signal transduction leading to cell growth, apoptosis, and differentiation.
The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. The antibody was conjugated with R-PE under optimum conditions, and unconjugated antibody and free PE were removed. Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
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