产品名称:APC 小鼠抗人 CD25 抗体;APC Mouse Anti-Human CD25
中文名称:APC 小鼠抗人 CD25 抗体
英文名称:APC Mouse Anti-Human CD25
APC Mouse Anti-Human CD25 产品介绍:
Material Number: 555434 Alternate Name: IL-2R; IL2RA; IL-2Rα; TCGFR; TAC antigen; p55 Size: 100 tests Vol. per Test: 20 µl Clone: M-A251 Isotype: Mouse IgG1, κ Reactivity: QC Testing: Human Workshop: IV A053 Storage Buffer: Aqueous buffered solution containing BSA and ≤0.09% sodium azide. APC Mouse Anti-Human CD25 Description:
The M-A251 monoclonal antibody specifically binds to the 55 kDa type I transmembrane glycoprotein known as the low-affinity interleukin-2 receptor alpha chain subunit (IL-2Rα). CD25 is expressed on regulatory T cells and on activated lymphocytes (T and B) and monocytes. It associates with the IL-2Rβ/CD122 and the IL-2Rγ/CD132 receptor chains to form the high-affinity IL-2R complex. CD25 expression on T and B lymphocytes is upregulated by antigenic or mitogenic stimulation. Soluble CD25/IL-2Rα is produced as a consequence of lymphocyte stimulation and is found in biological fluids following inflammatory responses.
The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. The antibody was conjugated to APC under optimum conditions, and unconjugated antibody and free APC were removed. Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
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