产品名称:PE-Cy™5 小鼠抗人 CD19 抗体;PE-Cy™5 Mouse Anti-Human CD19
中文名称:PE-Cy™5 小鼠抗人 CD19 抗体
英文名称:PE-Cy™5 Mouse Anti-Human CD19
PE-Cy™5 Mouse Anti-Human CD19 产品介绍:
Material Number: 555414 Size: 100 tests Vol. per Test: 20 µl Clone: HIB19 Isotype: Mouse IgG1, κ Reactivity: QC Testing: Human Workshop: V CD19.11 Storage Buffer: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
The HIB19 monoclonal antibody specificially binds to the 95 kDa type I transmembrane CD19 glycoprotein. CD19 is expressed during all stages of B-cell maturation and differentiation, except on plasma cells. CD19 is also present on follicular dendritic cells. It is not found on T cells or on normal granulocytes. CD19 is a signal transduction molecule that regulates B cell development, activation, proliferation and differentiation. It associates with the complement receptor 2 (CD21), TAPA-1 (CD81), Leu 13, and/or MHC class II to form a signal transduction complex on the surface of B cells. Anti-CD19 clone HIB19 partially blocks the binding of clone B43, another CD19-specific monoclonal antibody.
The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. The antibody was conjugated with PE-Cy5 under optimum conditions, and unconjugated antibody and free PE-Cy5 were removed. Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
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