产品名称:PE-Cy™5 小鼠抗人 CD4 抗体;PE-Cy™5 Mouse Anti-Human CD4
中文名称:PE-Cy™5 小鼠抗人 CD4 抗体
英文名称:PE-Cy™5 Mouse Anti-Human CD4
PE-Cy™5 Mouse Anti-Human CD4 产品介绍:
Material Number: 555348 Size: 100 tests Vol. per Test: 20 µl Clone: RPA-T4 Isotype: Mouse IgG1, κ Reactivity: QC Testing: Human Workshop: IV T114 Storage Buffer: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
The RPA-T4 clone reacts with CD4, a 59 kDa single-chain transmembrane glycoprotein [receptor for human immunodeficiency virus (HIV)] present on T-helper/inducer cell populations. This antibody binds to the D1 domain (CDR1 and CDR3 epitopes) of the CD4 antigen and reacts with approximately 80% of thymocytes and 45% of peripheral blood lymphocytes. CD4 is also present in low density on peripheral blood monocytes. RPA-T4 is capable of blocking HIV-1, gp120, and inhibits syncytium formation.
The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. The antibody was conjugated with PE-Cy5 (formerly known as BD Cy-Chrome™) under optimum conditions, and unconjugated antibody and free PE-Cy5 were removed. Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
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