产品名称:FITC 大鼠抗小鼠 CD3 Molecular Complex 抗体;FITC Rat Anti-Mouse CD3 Molecular Complex
中文名称:FITC 大鼠抗小鼠 CD3 Molecular Complex 抗体
英文名称:FITC Rat Anti-Mouse CD3 Molecular Complex
FITC Rat Anti-Mouse CD3 Molecular Complex 产品介绍:
Material Number: 555274 Size: 0.5 mg Concentration: 0.5 mg/ml Clone: 17A2 Immunogen: γδ TCR-positive T-T hybridoma D1 Isotype: Rat (SD) IgG2b, κ Reactivity: QC Testing: Mouse Storage Buffer: Aqueous buffered solution containing ≤0.09% sodium azide. FITC Rat Anti-Mouse CD3 Molecular Complex Description:
The 17A2 antibody reacts with the T-cell receptor-associated CD3 complex, which is expressed on many thymocytes and mature T lymphocytes. Plate-bound mAb 17A2 has been reported to induce IL-2 production by T cells in the absence of accessory cells. Binding of 17A2 antibody to T cells can be blocked by the anti-CD3e mAb 145-2C11, suggesting that 17A2 antibody recognizes an epitope of the CD3 epsilon chain. In vivo treatment with 17A2 mAb has been reported to partially deplete T lymphocytes and temporarily down-modulates CD3 expression on T cells.
The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. The antibody was conjugated with FITC under optimum conditions, and unreacted FITC was removed. Store undiluted at 4° C and protected from prolonged exposure to light. Do not freeze.
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