Purified Rat Anti-Mouse CD3 Molecular Complex

产品名称:Purified 大鼠抗小鼠 CD3 Molecular Complex 抗体；Purified Rat Anti-Mouse CD3 Molecular Complex

中文名称:Purified 大鼠抗小鼠 CD3 Molecular Complex 抗体

英文名称:Purified Rat Anti-Mouse CD3 Molecular Complex

Purified Rat Anti-Mouse CD3 Molecular Complex 产品介绍：

Material Number: 555273
Size: 0.5 mg
Concentration: 0.5 mg/ml
Clone: 17A2
Immunogen: γδ TCR-positive T-T hybridoma D1
Isotype: Rat (SD) IgG2b, κ
Reactivity: QC Testing: Mouse
Storage Buffer: Aqueous buffered solution containing ≤0.09% sodium azide.


Purified Rat Anti-Mouse CD3 Molecular Complex Description：

The 17A2 antibody reacts with the T-cell receptor-associated CD3 complex, which is expressed on many thymocytes and mature T 
lymphocytes. Plate-bound mAb 17A2 has been reported to induce IL-2 production by T cells in the absence of accessory cells. Binding of 
17A2 antibody to T cells can be blocked by the anti-CD3e mAb 145-2C11, suggesting that 17A2 antibody recognizes an epitope of the CD3 
epsilon chain. In vivo treatment with 17A2 mAb has been reported to partially deplete T lymphocytes and temporarily down-modulates CD3 
expression on T cells.

The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
Store undiluted at 4° C.